Recent Developments in Gas Chromatography-Mass Spectrometry


Greetings from the Journal of Chromatography and Separation techniques

A desire for miniaturization, flexibility, and faster results is the current global trend. Increase in the number of samples as well as regulatory requirements demands a focus on targeted and non‑targeted molecules in the areas of food safety and environmental health. Data handling solutions which are user friendly combined with smart instruments are helpful in preventive maintenance, ownership cost reduction, and simplifying workflows. Functions, such as automatic leak checks and troubleshooting diagnostics, allow operators to achieve better results faster, with fewer mistakes. Guiding users through preventative maintenance steps helps reduce sample reruns and unplanned downtime, greatly improving productivity. Remote connectivity is a future trend as digital transformation sweeps across analytical laboratory enterprises worldwide, driving resource deployment optimization. Remote connectivity and smart functionality are also invaluable when laboratory access is limited. Green chemistry and sustainable operations are also clear trends, and many new instruments are being designed to use less power, water, helium, and other natural resources.

Use of cost-efficient, oil-free Gas Chromatography-Mass Spectrometry is increasing. Another growing trend is moving applications to smaller, greener, and faster Gas Chromatographic systems with efficient direct heating technology. There is an increase in discovery-based approaches, where workflows that are typically seen in the “omics” fields are now expanding to other application areas. Recent trends in Gas Chromatography hyphenated with Mass Spectrometry include an increase in the use of triple quadrupole instruments, instrument miniaturization, and the migration towards multiclass methods of analysis. Detector sensitivity is outpacing analytical column and instrument designs in some cases, which should prompt further research. The future will see more and more GC systems coupled to mass spectrometers especially for food and environmental applications. Triple quadrupole GC-MS will be deployed more often. Micro-GC will continue to be valued for its convenient small form factor, rapid cycle times and its ability to verify calorific value as a measure of quality and economic valuation. The future of GC-MS will continue to focus on reduced analysis times, increased sensitivity, and platform miniaturization. MS will continue to increase in sensitivity, such as lower detection limits, through more efficient generation and transfer of ions.

Journal of Chromatography and Separation techniques is a peer-reviewed (refereed), academic, open-access, international scientific journal which provides a global scholarly platform to scientists, academicians and researchers to disseminate knowledge in the form of critical and informed articles related to separation science. If you are investigating on such novel and innovative areas of separation science then kindly consider contributing it to our upcoming issue Volume 12| Issue 1 (2021). Join hands with the Journal of Chromatography and Separation techniques in disseminating knowledge to the tertiary end users for the overall development in the field of separation science.

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Best Regards,
Managing Editor,
Journal of Chromatography and Separation Techniques