The Need for Improvements in Ultratrace Analysis for Environmental and Biological Analysis
Analytical chemists continue to develop methods for ultratrace-level analyses that are used by practitioners in areas such as environmental, human health studies, and process technology. However, questions continue to arise about whether the current methods are adequate. Global challenges that point to the need for significant disruptive technology in analytical chemistry should be addressed. For example, Endocrine disruptors either mimic or block the production of naturally occurring hormones. Compounds known to be endocrine disruptors include parabens, triclosan, polychlorinated biphenyls, bisphenol A, dioxin, flame retardants, plasticizers, and some pharmaceuticals. For many of these compounds, the minimum concentration level that will not affect the endocrine systems is not yet known. Similarly, oxidative stress on humans and wildlife because of exposure to ultratrace levels of pollutants is also of significant concern. Oxidative stress is suspected in neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.
Current analytical devices are not meeting all of the needs for ultratrace-level detection as described above. We must develop new means to lower the detection limits of organic and biological compounds. Clearly, further improvements in preconcentration capabilities with solid-phase extraction (SPE) and in chromatographic efficiency must occur. These improvements will facilitate improved detection limits for the analysis of small to medium organic compounds. In addition, MS detection limit improvements are needed. Analytical chemists must push forward to move detection limits lower and continue to improve the selectivity of analyses.
The Journal of Chromatography & Separation Techniques aims to disseminate knowledge and promote discussion through the publication of peer-reviewed, high quality research papers related to Separation science emphasizing on improvements in Ultratrace Analysis.
On behalf of the Journal of Chromatography & Separation Techniques, it is my great pleasure and honor to invite scientists, academicians and researchers from around the world to contribute their current research undertakings to our upcoming issue (Volume 11| Issue 2) on behalf of Editor-in-Chief.
The Journal covers high-level research education and development related to wide range of subjects including pharmaceutical, environmental, food and clinical sciences, reaching out to analytical scientists worldwide. Original research articles, reviews, short communications, and letters to the editors in the fields of chromatography and separation science are accepted. All submitted manuscripts are subjected to a stringent, rigorous peer review process and are carefully evaluated based on originality and clarity of exposition.
We cordially invite scientists, academicians and researchers from around the world to contribute their current research undertakings to our upcoming issue (Volume 11| Issue 2) on behalf of Editor-in-Chief.
Associate Managing Editor
Journal of Chromatography & Separation Techniques